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This example displays how areas within a editor instance can be disabled from editing using the noneditable plugin and some classes.
Below is all you need to setup the example.
<script type="text/javascript" src="<your installation path>/tiny_mce/tiny_mce.js"></script>
<script type="text/javascript">
tinyMCE.init({
theme : "advanced",
mode : "textareas",
plugins : "noneditable"
});
</script>
<form method="post" action="somepage">
<textarea name="content" style="width:100%">
<p>Editable content.</p>
<p class="mceNonEditable">Non editable content, can't be modified in IE or FF.</p>
<p>Editable content.</p>
<p class="mceNonEditable">Non editable content, can't be modified in IE or FF.</p>
</textarea>
</form>